Plasmid

Part:BBa_K1391028:Experience

Designed by: Shinjini Saha   Group: iGEM14_MIT   (2014-10-17)

We plan to downregulate BACE1 in order to reduce the amount of beta amyloid present in the brain. Our proposed method of downregulation is by inhibiting expression of the BACE1 gene using miRNA generators that are specific to different regions in the BACE1 gene.

miRNA Generator 1



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